Electrochemical borylation of carboxylic acids.
Proc Natl Acad Sci U S A
; 118(34)2021 08 24.
Article
en En
| MEDLINE
| ID: mdl-34404720
ABSTRACT
A simple electrochemically mediated method for the conversion of alkyl carboxylic acids to their borylated congeners is presented. This protocol features an undivided cell setup with inexpensive carbon-based electrodes and exhibits a broad substrate scope and scalability in both flow and batch reactors. The use of this method in challenging contexts is exemplified with a modular formal synthesis of jawsamycin, a natural product harboring five cyclopropane rings.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácidos Borónicos
/
Ácidos Carboxílicos
/
Electrodos
/
Técnicas Electroquímicas
Idioma:
En
Revista:
Proc Natl Acad Sci U S A
Año:
2021
Tipo del documento:
Article