Behavioral Inflexibility Across Two Neurogenetic Conditions: Down Syndrome and Fragile X Syndrome.
Am J Intellect Dev Disabil
; 126(5): 409-420, 2021 09 01.
Article
en En
| MEDLINE
| ID: mdl-34428269
ABSTRACT
Behavioral inflexibility (BI) has been highlighted to occur across genetic and neurodevelopmental disorders. This study characterized BI in two common neurogenetic conditions Fragile X syndrome (FXS) and Down syndrome (DS). Caregivers of children with FXS (N = 56; with ASD = 28; FXS only = 28) and DS (N = 146) completed the Behavioral Inflexibility Scale (BIS) via an online survey. Total BIS scores were higher in FXS+ASD than both FXS only and DS (p <.001). Most endorsed items were similar across the three groups, but scores were higher in the FXS+ASD group. In all groups, BI associated with other clinical variables (receptive behaviors, anxiety, social communication). The current data suggest that BI is variable across neurogenetic conditions and higher in individuals with comorbid ASD.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Down
/
Trastorno del Espectro Autista
/
Síndrome del Cromosoma X Frágil
Límite:
Child
/
Humans
Idioma:
En
Revista:
Am J Intellect Dev Disabil
Asunto de la revista:
TRANSTORNOS MENTAIS
Año:
2021
Tipo del documento:
Article