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TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.
Gonzalez-Buendia, Edgar; Zhao, Junfei; Wang, Lu; Mukherjee, Subhas; Zhang, Daniel; Arrieta, Víctor A; Feldstein, Eric; Kane, J Robert; Kang, Seong Jae; Lee-Chang, Catalina; Mahajan, Aayushi; Chen, Li; Realubit, Ronald; Karan, Charles; Magnuson, Lisa; Horbinski, Craig; Marshall, Stacy A; Sarkaria, Jann N; Mohyeldin, Ahmed; Nakano, Ichiro; Bansal, Mukesh; James, Charles D; Brat, Daniel J; Ahmed, Atique; Canoll, Peter; Rabadan, Raul; Shilatifard, Ali; Sonabend, Adam M.
Afiliación
  • Gonzalez-Buendia E; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Zhao J; Department of Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York.
  • Wang L; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Mukherjee S; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Zhang D; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Arrieta VA; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Feldstein E; PECEM, Facultad de Medicina, Universidad Nacional Autónoma de México, México.
  • Kane JR; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Kang SJ; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Lee-Chang C; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Mahajan A; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Chen L; Department of Pathology and Cell Biology, Columbia University, New York, New York.
  • Realubit R; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Karan C; High-Throughput Screening Genome Center, Columbia University, New York, New York.
  • Magnuson L; High-Throughput Screening Genome Center, Columbia University, New York, New York.
  • Horbinski C; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Marshall SA; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Sarkaria JN; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Mohyeldin A; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Nakano I; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
  • Bansal M; Department of Neurosurgery, Ohio State University, Columbus, Ohio.
  • James CD; Department of Neurosurgery, University of Alabama, Birmingham, Alabama.
  • Brat DJ; Department of Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York.
  • Ahmed A; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Canoll P; Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Rabadan R; Department of Neurosurgery, Feinberg School of Medicine, Northwestern University and Northwestern Medicine Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
  • Shilatifard A; Department of Pathology and Cell Biology, Columbia University, New York, New York.
  • Sonabend AM; Department of Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York.
Clin Cancer Res ; 27(20): 5669-5680, 2021 10 15.
Article en En | MEDLINE | ID: mdl-34433651
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Neoplasias Encefálicas / Intrones / Regiones Promotoras Genéticas / ADN-Topoisomerasas de Tipo II / Epigénesis Genética / Proteínas de Unión a Poli-ADP-Ribosa / Glioma Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Neoplasias Encefálicas / Intrones / Regiones Promotoras Genéticas / ADN-Topoisomerasas de Tipo II / Epigénesis Genética / Proteínas de Unión a Poli-ADP-Ribosa / Glioma Límite: Animals / Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2021 Tipo del documento: Article Pais de publicación: Estados Unidos