An Overview of Vaccines against SARS-CoV-2 in the COVID-19 Pandemic Era.
Pathogens
; 10(8)2021 Aug 14.
Article
en En
| MEDLINE
| ID: mdl-34451494
ABSTRACT
The emergence of SARS-CoV-2 in late 2019 led to the COVID-19 pandemic all over the world. When the virus was first isolated and its genome was sequenced in the early months of 2020, the efforts to develop a vaccine began. Based on prior well-known knowledge about coronavirus, the SARS-CoV-2 spike (S) protein was selected as the main target. Currently, more than one hundred vaccines are being investigated and several of them are already authorized by medical agencies. This review summarizes and compares the current knowledge about main approaches for vaccine development, focusing on those authorized and specifically their immunogenicity, efficacy preventing severe disease, adverse side effects, protection, and ability to cope with emergent SARS-CoV-2 variants.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Pathogens
Año:
2021
Tipo del documento:
Article
País de afiliación:
España
Pais de publicación:
CH
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SUIZA
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SUÍÇA
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SWITZERLAND