Microsatellite Markers in Biobanking: A New Multiplexed Assay.
Biopreserv Biobank
; 19(5): 438-443, 2021 Oct.
Article
en En
| MEDLINE
| ID: mdl-34468209
ABSTRACT
Microsatellites, or MSATs, offer a fast and cost-effective way for biobanks to establish a biospecimen genetic profile. Importantly, this genetic profile can be used to authenticate multiple submissions derived from the same individual as well as biospecimens derived from the same original sample submission over time. While the Certificate of Confidentiality provided by the National Institutes of Health offers some meaningful protection to prevent the disclosure of potentially identifiable information to entities within the United States, we consider, in this study, the potential to offer additional protection to participants who choose to donate to biobanks by minimizing the use of forensic Combined DNA Index System (CODIS) MSAT markers in biobanking. To this end, we report the design and validation of a new multiplexed MSAT assay that does not include CODIS markers for use in biobanking operations and quality control management.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bancos de Muestras Biológicas
/
Confidencialidad
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Biopreserv Biobank
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos