Highly sialylated mucin-type glycopeptide from porcine intestinal mucosa after heparin extraction: O-glycan profiling and immunological activity evaluation.

Zhang, Xin; Wang, Chen; Han, Qing; Chen, Xuan; Li, Guoyun; Yu, Guangli

Zhang, Xin; Wang, Chen; Han, Qing; Chen, Xuan; Li, Guoyun; Yu, Guangli.

Afiliación

Zhang X; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
Wang C; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
Han Q; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
Chen X; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.
Li G; Key Laboratory of Marine Drugs of Ministry of Education, Shandong Provincial Key Laboratory of Glycoscience and Glycotechnology, School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China. liguoyun@ouc.edu.cn.
Yu G; Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao, 266237, China. liguoyun@ouc.edu.cn.

Glycoconj J ; 38(5): 527-537, 2021 10.

Article en En | MEDLINE | ID: mdl-34480673

Asunto(s)

Heparina/química; Mucosa Intestinal/química; Mucosa Intestinal/metabolismo; Macrófagos/efectos de los fármacos; Mucinas/química; Mucinas/farmacología; Animales; Heparina/metabolismo; Macrófagos/inmunología; Ratones; Células RAW 264.7; Porcinos

Palabras clave

Immunoregulatory; O-glycans; Porcine intestinal mucin; Sialic acid; Structural characterization

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Heparina / Mucosa Intestinal / Macrófagos / Mucinas Límite: Animals Idioma: En Revista: Glycoconj J Asunto de la revista: BIOQUIMICA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: China

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