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Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
Min, Josine L; Hemani, Gibran; Hannon, Eilis; Dekkers, Koen F; Castillo-Fernandez, Juan; Luijk, René; Carnero-Montoro, Elena; Lawson, Daniel J; Burrows, Kimberley; Suderman, Matthew; Bretherick, Andrew D; Richardson, Tom G; Klughammer, Johanna; Iotchkova, Valentina; Sharp, Gemma; Al Khleifat, Ahmad; Shatunov, Aleksey; Iacoangeli, Alfredo; McArdle, Wendy L; Ho, Karen M; Kumar, Ashish; Söderhäll, Cilla; Soriano-Tárraga, Carolina; Giralt-Steinhauer, Eva; Kazmi, Nabila; Mason, Dan; McRae, Allan F; Corcoran, David L; Sugden, Karen; Kasela, Silva; Cardona, Alexia; Day, Felix R; Cugliari, Giovanni; Viberti, Clara; Guarrera, Simonetta; Lerro, Michael; Gupta, Richa; Bollepalli, Sailalitha; Mandaviya, Pooja; Zeng, Yanni; Clarke, Toni-Kim; Walker, Rosie M; Schmoll, Vanessa; Czamara, Darina; Ruiz-Arenas, Carlos; Rezwan, Faisal I; Marioni, Riccardo E; Lin, Tian; Awaloff, Yvonne; Germain, Marine.
Afiliación
  • Min JL; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. josine.min@bristol.ac.uk.
  • Hemani G; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. josine.min@bristol.ac.uk.
  • Hannon E; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Dekkers KF; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Castillo-Fernandez J; University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, UK.
  • Luijk R; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
  • Carnero-Montoro E; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Lawson DJ; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
  • Burrows K; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Suderman M; Pfizer-University of Granada-Andalusian Government Center for Genomics and Oncological Research, Granada, Spain.
  • Bretherick AD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Richardson TG; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Klughammer J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Iotchkova V; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Sharp G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Al Khleifat A; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Shatunov A; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Iacoangeli A; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • McArdle WL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Ho KM; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Kumar A; MRC Weatherall Institute of Molecular Medicine, Oxford, UK.
  • Söderhäll C; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Soriano-Tárraga C; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Giralt-Steinhauer E; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Kazmi N; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • Mason D; Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, UK.
  • McRae AF; Department of Biostatistics and Health Informatics, King's College London, London, UK.
  • Corcoran DL; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Sugden K; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Kasela S; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Cardona A; Chronic Disease Epidemiology unit, Swiss Tropical and Public Health Institute, Basel, Switzerland.
  • Day FR; University of Basel, Basel, Switzerland.
  • Cugliari G; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
  • Viberti C; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.
  • Guarrera S; Neurology Department, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.
  • Lerro M; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Gupta R; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Bollepalli S; Bradford Institute for Health Research, Bradford, UK.
  • Mandaviya P; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia.
  • Zeng Y; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
  • Clarke TK; Center for Genomic and Computational Biology, Duke University, Durham, NC, USA.
  • Walker RM; Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
  • Schmoll V; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.
  • Czamara D; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Ruiz-Arenas C; Department of Genetics, University of Cambridge, Cambridge, UK.
  • Rezwan FI; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Marioni RE; Department of Medical Sciences, University of Turin, Turin, Italy.
  • Lin T; Italian Institute for Genomic Medicine, Turin, Italy.
  • Awaloff Y; Department of Medical Sciences, University of Turin, Turin, Italy.
  • Germain M; Italian Institute for Genomic Medicine, Turin, Italy.
Nat Genet ; 53(9): 1311-1321, 2021 09.
Article en En | MEDLINE | ID: mdl-34493871
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Regulación de la Expresión Génica / Metilación de ADN / Predisposición Genética a la Enfermedad / Sitios de Carácter Cuantitativo Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Regulación de la Expresión Génica / Metilación de ADN / Predisposición Genética a la Enfermedad / Sitios de Carácter Cuantitativo Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos