Effects of Cardiolipin on the Conformational Dynamics of Membrane-Anchored Bcl-xL.

Tyagi, Vivek; Vasquez-Montes, Victor; Freites, J Alfredo; Kyrychenko, Alexander; Tobias, Douglas J; Ladokhin, Alexey S

Tyagi, Vivek; Vasquez-Montes, Victor; Freites, J Alfredo; Kyrychenko, Alexander; Tobias, Douglas J; Ladokhin, Alexey S.

Afiliación

Tyagi V; Department of Materials Science and Engineering, University of California, Irvine, CA 92697, USA.
Vasquez-Montes V; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Freites JA; Department of Chemistry, University of California, Irvine, CA 92697, USA.
Kyrychenko A; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Tobias DJ; Institute of Chemistry & School of Chemistry, V. N. Karazin Kharkiv National University, 4 Svobody Square, 61022 Kharkiv, Ukraine.
Ladokhin AS; Department of Chemistry, University of California, Irvine, CA 92697, USA.

Int J Mol Sci ; 22(17)2021 Aug 30.

Article en En | MEDLINE | ID: mdl-34502299

Asunto(s)

Cardiolipinas/metabolismo; Membrana Celular/metabolismo; Conformación Proteica; Proteína bcl-X/química; Proteína bcl-X/metabolismo; Apoptosis; Cardiolipinas/química; Humanos; Simulación de Dinámica Molecular

Palabras clave

BCL-2 proteins; BH3-binding site; Bcl-xL; apoptotic regulation; cardiolipin; molecular dynamics simulations; proteinmembrane interactions

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Conformación Proteica / Cardiolipinas / Membrana Celular / Proteína bcl-X Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

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