Exogenous Aß seeds induce Aß depositions in the blood vessels rather than the brain parenchyma, independently of Aß strain-specific information.

Hamaguchi, Tsuyoshi; Kim, Jee Hee; Hasegawa, Akane; Goto, Ritsuko; Sakai, Kenji; Ono, Kenjiro; Itoh, Yoshinori; Yamada, Masahito

Hamaguchi, Tsuyoshi; Kim, Jee Hee; Hasegawa, Akane; Goto, Ritsuko; Sakai, Kenji; Ono, Kenjiro; Itoh, Yoshinori; Yamada, Masahito.

Afiliación

Hamaguchi T; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Kim JH; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Hasegawa A; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Goto R; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Sakai K; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Ono K; Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
Itoh Y; Department of Internal Medicine, Division of Neurology, Showa University School of Medicine, Tokyo, Japan.
Yamada M; Yokufukai Geriatric Hospital, Tokyo, Japan.

Acta Neuropathol Commun ; 9(1): 151, 2021 09 10.

Article en En | MEDLINE | ID: mdl-34507620

Asunto(s)

Péptidos beta-Amiloides/administración & dosificación; Péptidos beta-Amiloides/metabolismo; Encéfalo/irrigación sanguínea; Encéfalo/metabolismo; Tejido Parenquimatoso/irrigación sanguínea; Tejido Parenquimatoso/metabolismo; Anciano; Anciano de 80 o más Años; Precursor de Proteína beta-Amiloide/metabolismo; Animales; Encéfalo/patología; Femenino; Humanos; Masculino; Ratones; Ratones Transgénicos; Tejido Parenquimatoso/patología; Especificidad de la Especie

Palabras clave

Alzheimer's disease; Amyloid ß peptide; Cerebral amyloid angiopathy; Iatrogenic; Strain; Transmission

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Encéfalo / Péptidos beta-Amiloides / Tejido Parenquimatoso Límite: Aged / Aged80 / Animals / Female / Humans / Male Idioma: En Revista: Acta Neuropathol Commun Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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