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Drugs in Focus: Octreotide Use in Children With Gastrointestinal Disorders.
Mas, Emmanuel; Borrelli, Osvaldo; Broekaert, Ilse; de-Carpi, J Martin; Dolinsek, Jernej; Miele, Erasmo; Pienar, Corina; Koninckx, C Ribes; Thomassen, Ruth-Anne; Thomson, Mike; Tzivinikos, Christo; Benninga, Marc A.
Afiliación
  • Mas E; Unité de Gastroentérologie, Hépatologie, Nutrition, Diabétologie et Maladies Héréditaires du Métabolisme, Hôpital des Enfants, CHU de Toulouse; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, UPS, Toulouse, France.
  • Borrelli O; Department of Paediatric Gastroenterology, Neurogastroenterology and Motility Unit, Great Ormond Street Hospital, London, UK.
  • Broekaert I; Department of Paediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • de-Carpi JM; Department of Paediatric Gastroenterology, Hepatology and Nutrition, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Dolinsek J; Department of Paediatrics, University Medical Centre Maribor, Maribor, Slovenia.
  • Miele E; Department of Translational Medical Science, Section of Paediatrics, University of Naples "Federico II", Naples Italy.
  • Pienar C; Department of Paediatrics, 2 Paediatric Clinic, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania.
  • Koninckx CR; Paediatric Gastroenterology, La Fe University Hospital, Valencia, Spain.
  • Thomassen RA; Department of Paediatric Medicine, Division of Paediatric and Adolescent Medicine, Oslo University Hospital, Oslo, Norway.
  • Thomson M; Centre for Paediatric Gastroenterology, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, UK.
  • Tzivinikos C; Department of Paediatric Gastroenterology, Al Jalila Children's Specialty Hospital, Dubai, UAE.
  • Benninga MA; Department of Paediatric Gastroenterology and Nutrition, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
J Pediatr Gastroenterol Nutr ; 74(1): 1-6, 2022 01 01.
Article en En | MEDLINE | ID: mdl-34508049
ABSTRACT
ABSTRACT Octreotide, a somatostatin analogue, has been used for more than 20 years in children with gastrointestinal bleeding, chylothorax or chylous ascites, intestinal lymphangiectasia, pancreatitis, intestinal dysmotility, and severe diarrhoea; however, until now, there is a lack of randomised clinical trials evaluating the efficacy of this compound in childhood. Hence, we aimed to review the literature in order to determine the evidence of its use and safety in children, using PubMed from 2000 to 2021 with the search terms "octreotide" and "children" and "bleeding or chylous ascites or chylothorax or acute pancreatitis or lymphangiectasia or diarrhoea or intestinal dysmotility".
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatitis / Preparaciones Farmacéuticas / Enfermedades Gastrointestinales Tipo de estudio: Clinical_trials Límite: Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2022 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pancreatitis / Preparaciones Farmacéuticas / Enfermedades Gastrointestinales Tipo de estudio: Clinical_trials Límite: Child / Humans Idioma: En Revista: J Pediatr Gastroenterol Nutr Año: 2022 Tipo del documento: Article País de afiliación: Francia