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Virus-induced senescence is a driver and therapeutic target in COVID-19.
Lee, Soyoung; Yu, Yong; Trimpert, Jakob; Benthani, Fahad; Mairhofer, Mario; Richter-Pechanska, Paulina; Wyler, Emanuel; Belenki, Dimitri; Kaltenbrunner, Sabine; Pammer, Maria; Kausche, Lea; Firsching, Theresa C; Dietert, Kristina; Schotsaert, Michael; Martínez-Romero, Carles; Singh, Gagandeep; Kunz, Séverine; Niemeyer, Daniela; Ghanem, Riad; Salzer, Helmut J F; Paar, Christian; Mülleder, Michael; Uccellini, Melissa; Michaelis, Edward G; Khan, Amjad; Lau, Andrea; Schönlein, Martin; Habringer, Anna; Tomasits, Josef; Adler, Julia M; Kimeswenger, Susanne; Gruber, Achim D; Hoetzenecker, Wolfram; Steinkellner, Herta; Purfürst, Bettina; Motz, Reinhard; Di Pierro, Francesco; Lamprecht, Bernd; Osterrieder, Nikolaus; Landthaler, Markus; Drosten, Christian; García-Sastre, Adolfo; Langer, Rupert; Ralser, Markus; Eils, Roland; Reimann, Maurice; Fan, Dorothy N Y; Schmitt, Clemens A.
Afiliación
  • Lee S; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Yu Y; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Trimpert J; Deutsches Konsortium für Translationale Krebsforschung (German Cancer Consortium), Partner Site Berlin, Berlin, Germany.
  • Benthani F; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Mairhofer M; Institute of Virology, Freie Universität Berlin, Berlin, Germany.
  • Richter-Pechanska P; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Wyler E; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Belenki D; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Kaltenbrunner S; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Pammer M; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Kausche L; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Firsching TC; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Dietert K; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Schotsaert M; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Martínez-Romero C; Department of Hematology and Oncology, Kepler University Hospital, Linz, Austria.
  • Singh G; Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
  • Kunz S; Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
  • Niemeyer D; Veterinary Centre for Resistance Research, Freie Universität Berlin, Berlin, Germany.
  • Ghanem R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Salzer HJF; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Paar C; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Mülleder M; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Uccellini M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Michaelis EG; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Khan A; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Lau A; Institute of Virology, German Center for Infection Research (DZIF), Charité-Universitätsmedizin,, Berlin, Germany.
  • Schönlein M; Department of Hematology and Oncology, Kepler University Hospital, Linz, Austria.
  • Habringer A; Department of Pulmonology, Kepler University Hospital, Linz, Austria.
  • Tomasits J; Laboratory Medicine, Kepler University Hospital, Linz, Austria.
  • Adler JM; Core Facility - High-Throughput Mass Spectrometry and Department of Biochemistry, Charité - Universitätsmedizin, Berlin, Germany.
  • Kimeswenger S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Gruber AD; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Hoetzenecker W; Regeneron Pharmaceuticals, New York, NY, USA.
  • Steinkellner H; Institute of Pathology, Charité - Universitätsmedizin, Berlin, Germany.
  • Purfürst B; Department of Chemistry, University of Oxford, Oxford, UK.
  • Motz R; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Di Pierro F; Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum (MKFZ), Charité - Universitätsmedizin, Berlin, Germany.
  • Lamprecht B; Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Osterrieder N; Laboratory Medicine, Kepler University Hospital, Linz, Austria.
  • Landthaler M; Laboratory Medicine, Kepler University Hospital, Linz, Austria.
  • Drosten C; Institute of Virology, Freie Universität Berlin, Berlin, Germany.
  • García-Sastre A; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Langer R; Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
  • Ralser M; Medical Faculty, Johannes Kepler University, Linz, Austria.
  • Eils R; Department of Dermatology, Kepler University Hospital, Linz, Austria.
  • Reimann M; Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Fan DNY; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.
  • Schmitt CA; Institute of Pathology, Kepler University Hospital, Linz, Austria.
Nature ; 599(7884): 283-289, 2021 11.
Article en En | MEDLINE | ID: mdl-34517409
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Senescencia Celular / Terapia Molecular Dirigida / SARS-CoV-2 / COVID-19 / Tratamiento Farmacológico de COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Añadir a Mi BVS
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Senescencia Celular / Terapia Molecular Dirigida / SARS-CoV-2 / COVID-19 / Tratamiento Farmacológico de COVID-19 Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Alemania