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Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation.
Jirkovský, Eduard; Jirkovská, Anna; Bavlovic-Piskácková, Hana; Skalická, Veronika; Pokorná, Zuzana; Karabanovich, Galina; Kollárová-Brázdová, Petra; Kubes, Jan; Lencová-Popelová, Olga; Mazurová, Yvona; Adamcová, Michaela; Lyon, Alexander R; Roh, Jaroslav; Simunek, Tomás; Sterbová-Kovaríková, Petra; Sterba, Martin.
Afiliación
  • Jirkovský E; Department of Pharmacology, Faculty of Medicine in Hradec Králové (E.J., Z.P., P.K.-B., O.L.-P., M.S.), Charles University, Czech Republic.
  • Jirkovská A; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové (E.J.), Charles University, Czech Republic.
  • Bavlovic-Piskácková H; Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové (A.J., V.S., J.K., T.S.), Charles University, Czech Republic.
  • Skalická V; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové (H.B.-P., P.S.-K.), Charles University, Czech Republic.
  • Pokorná Z; Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové (A.J., V.S., J.K., T.S.), Charles University, Czech Republic.
  • Karabanovich G; Department of Pharmacology, Faculty of Medicine in Hradec Králové (E.J., Z.P., P.K.-B., O.L.-P., M.S.), Charles University, Czech Republic.
  • Kollárová-Brázdová P; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové (G.K., J.R.), Charles University, Czech Republic.
  • Kubes J; Department of Pharmacology, Faculty of Medicine in Hradec Králové (E.J., Z.P., P.K.-B., O.L.-P., M.S.), Charles University, Czech Republic.
  • Lencová-Popelová O; Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové (A.J., V.S., J.K., T.S.), Charles University, Czech Republic.
  • Mazurová Y; Department of Pharmacology, Faculty of Medicine in Hradec Králové (E.J., Z.P., P.K.-B., O.L.-P., M.S.), Charles University, Czech Republic.
  • Adamcová M; Department of Histology and Embryology, Faculty of Medicine in Hradec Králové (Y.M.), Charles University, Czech Republic.
  • Lyon AR; Department of Physiology, Faculty of Medicine in Hradec Králové (M.A.), Charles University, Czech Republic.
  • Roh J; Department of Cardiology, Royal Brompton Hospital and Faculty of Medicine, National Heart and Lung Institute, Imperial College London, United Kingdom (A.R.L.).
  • Simunek T; Department of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové (G.K., J.R.), Charles University, Czech Republic.
  • Sterbová-Kovaríková P; Department of Biochemical Sciences, Faculty of Pharmacy in Hradec Králové (A.J., V.S., J.K., T.S.), Charles University, Czech Republic.
  • Sterba M; Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové (H.B.-P., P.S.-K.), Charles University, Czech Republic.
Circ Heart Fail ; 14(11): e008209, 2021 11.
Article en En | MEDLINE | ID: mdl-34551586
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antraciclinas / Inhibidores de Topoisomerasa II / Dexrazoxano / Cardiotoxicidad / Insuficiencia Cardíaca Límite: Humans Idioma: En Revista: Circ Heart Fail Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antraciclinas / Inhibidores de Topoisomerasa II / Dexrazoxano / Cardiotoxicidad / Insuficiencia Cardíaca Límite: Humans Idioma: En Revista: Circ Heart Fail Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: República Checa