Monoclonal Antibodies Casirivimab and Imdevimab in Pregnancy for Coronavirus Disease 2019 (COVID-19).
Obstet Gynecol
; 138(6): 937-939, 2021 12 01.
Article
en En
| MEDLINE
| ID: mdl-34583385
ABSTRACT
BACKGROUND:
For unvaccinated individuals with mild-to-moderate coronavirus disease 2019 (COVID-19), monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) decrease the risk of severe disease and hospitalization. We describe the use of the monoclonal antibodies casirivimab and imdevimab for COVID-19 in pregnancy. CASE Two unvaccinated pregnant individuals presented with moderate COVID-19, one in the second trimester and one in third trimester; both met criteria for outpatient management. To decrease the risk for severe disease, they were treated with casirivimab and imdevimab. Neither experienced an adverse drug reaction, and neither progressed to severe disease.CONCLUSION:
Monoclonal antibodies such as casirivimab and imdevimab, approved under an emergency use authorization, should be considered in unvaccinated pregnant individuals with mild-to-moderate COVID-19 to decrease the risk of severe disease.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antivirales
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Complicaciones Infecciosas del Embarazo
/
Anticuerpos Neutralizantes
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Anticuerpos Monoclonales Humanizados
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Tratamiento Farmacológico de COVID-19
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Obstet Gynecol
Año:
2021
Tipo del documento:
Article