Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells.

Chen, Lu; Zhang, Min; Fang, Lei; Yang, Xiaoli; Cao, Ning; Xu, Liyang; Shi, Lihua; Cao, Ying

Chen, Lu; Zhang, Min; Fang, Lei; Yang, Xiaoli; Cao, Ning; Xu, Liyang; Shi, Lihua; Cao, Ying.

Afiliación

Chen L; Research Institute of Nanjing University in Shenzhen, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Zhang M; Research Institute of Nanjing University in Shenzhen, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Fang L; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Yang X; Research Institute of Nanjing University in Shenzhen, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Cao N; Research Institute of Nanjing University in Shenzhen, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Xu L; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Shi L; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China.
Cao Y; Research Institute of Nanjing University in Shenzhen, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China; Jiangsu Key Laboratory of Molecular Medicine of the Medical School, Nanjing University, Nanjing, China. Elec

J Biol Chem ; 297(5): 101275, 2021 11.

Article en En | MEDLINE | ID: mdl-34619150

Asunto(s)

Proteínas de Neoplasias/metabolismo; Células Madre Neoplásicas/metabolismo; Células-Madre Neurales/metabolismo; Complejo de la Endopetidasa Proteasomal/metabolismo; Proteína-Arginina N-Metiltransferasas/metabolismo; Proteínas Represoras/metabolismo; Ribosomas/metabolismo; Células A549; Animales; Células Hep G2; Humanos; Ratones; Ratones Noqueados; Proteínas de Neoplasias/genética; Células Madre Neoplásicas/patología; Células-Madre Neurales/patología; Complejo de la Endopetidasa Proteasomal/genética; Proteína-Arginina N-Metiltransferasas/genética; Proteínas Represoras/genética; Ribosomas/genética

Palabras clave

PRMT1; USP7; cancer cell; cell differentiation; deubiquitination; neural stem cell (NSC); neural stemness; proteasome; ribosome; tumorigenicity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína-Arginina N-Metiltransferasas / Proteínas Represoras / Ribosomas / Células Madre Neoplásicas / Complejo de la Endopetidasa Proteasomal / Células-Madre Neurales / Proteínas de Neoplasias Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

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