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CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial.
Cordoba, Shaun; Onuoha, Shimobi; Thomas, Simon; Pignataro, Daniela Soriano; Hough, Rachael; Ghorashian, Sara; Vora, Ajay; Bonney, Denise; Veys, Paul; Rao, Kanchan; Lucchini, Giovanna; Chiesa, Robert; Chu, Jan; Clark, Liz; Fung, Mei Mei; Smith, Koval; Peticone, Carlotta; Al-Hajj, Muhammad; Baldan, Vania; Ferrari, Mathieu; Srivastava, Saket; Jha, Ram; Arce Vargas, Frederick; Duffy, Kevin; Day, William; Virgo, Paul; Wheeler, Lucy; Hancock, Jeremy; Farzaneh, Farzin; Domning, Sabine; Zhang, Yiyun; Khokhar, Nushmia Z; Peddareddigari, Vijay G R; Wynn, Robert; Pule, Martin; Amrolia, Persis J.
Afiliación
  • Cordoba S; Autolus PLC, London, UK.
  • Onuoha S; Autolus PLC, London, UK.
  • Thomas S; Autolus PLC, London, UK.
  • Pignataro DS; Autolus PLC, London, UK.
  • Hough R; Department of Haematology, University College London Hospitals NHS Trust, London, UK.
  • Ghorashian S; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Vora A; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Bonney D; Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, UK.
  • Veys P; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Rao K; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Lucchini G; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Chiesa R; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Chu J; Departments of Bone Marrow Transplant and Haematology, Great Ormond Street Hospital for Children, London, UK.
  • Clark L; Autolus PLC, London, UK.
  • Fung MM; Autolus PLC, London, UK.
  • Smith K; Autolus PLC, London, UK.
  • Peticone C; Autolus PLC, London, UK.
  • Al-Hajj M; Autolus PLC, London, UK.
  • Baldan V; Autolus PLC, London, UK.
  • Ferrari M; Autolus PLC, London, UK.
  • Srivastava S; Autolus PLC, London, UK.
  • Jha R; Autolus PLC, London, UK.
  • Arce Vargas F; Autolus PLC, London, UK.
  • Duffy K; Autolus PLC, London, UK.
  • Day W; Autolus PLC, London, UK.
  • Virgo P; Department of Immunology and Immunogenetics, North Bristol NHS Trust, Bristol, UK.
  • Wheeler L; Department of Immunology and Immunogenetics, North Bristol NHS Trust, Bristol, UK.
  • Hancock J; Bristol Genetics Laboratory, North Bristol NHS Trust, Bristol, UK.
  • Farzaneh F; Rayne Institute, Kings College London, London, UK.
  • Domning S; Rayne Institute, Kings College London, London, UK.
  • Zhang Y; Autolus PLC, London, UK.
  • Khokhar NZ; Autolus PLC, London, UK.
  • Peddareddigari VGR; Autolus PLC, London, UK.
  • Wynn R; Department of Blood and Marrow Transplant, Royal Manchester Children's Hospital, Manchester, UK.
  • Pule M; Autolus PLC, London, UK. m.pule@autolus.com.
  • Amrolia PJ; Cancer Institute, University College London, London, UK. m.pule@autolus.com.
Nat Med ; 27(10): 1797-1805, 2021 10.
Article en En | MEDLINE | ID: mdl-34642489
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Antígenos CD19 / Lectina 2 Similar a Ig de Unión al Ácido Siálico / Receptores Quiméricos de Antígenos Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Antígenos CD19 / Lectina 2 Similar a Ig de Unión al Ácido Siálico / Receptores Quiméricos de Antígenos Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos