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Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.
Gangaev, Anastasia; Rozeman, Elisa A; Rohaan, Maartje W; Isaeva, Olga I; Philips, Daisy; Patiwael, Sanne; van den Berg, Joost H; Ribas, Antoni; Schadendorf, Dirk; Schilling, Bastian; Schumacher, Ton N; Blank, Christian U; Haanen, John B A G; Kvistborg, Pia.
Afiliación
  • Gangaev A; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Rozeman EA; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Rohaan MW; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Isaeva OI; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Philips D; Department of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Patiwael S; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • van den Berg JH; Department of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Ribas A; Oncode Institute, Utrecht, 3521 AL, The Netherlands.
  • Schadendorf D; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Schilling B; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Schumacher TN; Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, 1066 CX, The Netherlands.
  • Blank CU; University of California Los Angeles Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095.
  • Haanen JBAG; Department of Dermatology, University Hospital Duisburg-Essen, Essen D-45147, Germany.
  • Kvistborg P; Department of Dermatology, University Hospital Duisburg-Essen, Essen D-45147, Germany.
Proc Natl Acad Sci U S A ; 118(43)2021 10 26.
Article en En | MEDLINE | ID: mdl-34670835

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Inhibidores de Puntos de Control Inmunológico / Melanoma Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Antígeno CTLA-4 / Receptor de Muerte Celular Programada 1 / Inhibidores de Puntos de Control Inmunológico / Melanoma Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos