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Identification of an AXL kinase inhibitor in triple-negative breast cancer by structure-based virtual screening and bioactivity test.
Li, Pei; Niu, Yuzhen; Li, Shuyan; Zu, Xuyu; Xiao, Maoyu; Yin, Liyang; Feng, Jianbo; He, Jun; Shen, Yingying.
Afiliación
  • Li P; The First Affiliated Hospital, Department of Oncology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
  • Niu Y; Key Laboratory of Oncology and Molecular Pathology of Hunan Province, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
  • Li S; School of Life Sciences, Shandong University of Technology, Zibo, Shandong, China.
  • Zu X; College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, China.
  • Xiao M; The First Affiliated Hospital, Department of Oncology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
  • Yin L; Key Laboratory of Oncology and Molecular Pathology of Hunan Province, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
  • Feng J; The First Affiliated Hospital, Department of Oncology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
  • He J; Key Laboratory of Oncology and Molecular Pathology of Hunan Province, The First Affiliated Hospital of University of South China, Hengyang, Hunan, China.
  • Shen Y; The First Affiliated Hospital, Department of Oncology, Hengyang Medical School, University of South China, Hengyang, Hunan, China.
Chem Biol Drug Des ; 99(2): 222-232, 2022 02.
Article en En | MEDLINE | ID: mdl-34679238

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas / Neoplasias de la Mama Triple Negativas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Female / Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Inhibidores de Proteínas Quinasas / Neoplasias de la Mama Triple Negativas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Female / Humans Idioma: En Revista: Chem Biol Drug Des Asunto de la revista: BIOQUIMICA / FARMACIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido