A Generative Adversarial Network technique for high-quality super-resolution reconstruction of cardiac magnetic resonance images.

PURPOSE: In this paper, we proposed a Denoising Super-resolution Generative Adversarial Network (DnSRGAN) method for high-quality super-resolution reconstruction of noisy cardiac magnetic resonance (CMR) images. METHODS: The proposed method is based on feed-forward denoising convolutional neural network (DnCNN) and SRGAN architecture. Firstly, we used a feed-forward denoising neural network to pre-denoise the CMR image to ensure that the input is a clean image. Secondly, we use the gradient penalty (GP) method to solve the problem of the discriminator gradient disappearing, which improves the convergence speed of the model. Finally, a new loss function is added to the original SRGAN loss function to monitor GAN gradient descent to achieve more stable and efficient model training, thereby providing higher perceptual quality for the super-resolution of CMR images. RESULTS: We divided the tested cardiac images into 3 groups, each group of 25 images. Then, we calculated the Peak Signal to Noise Ratio (PSNR) /Structural Similarity (SSIM) between Ground Truth (GT) and the images generated by super-resolution, used them to evaluate our model. We compared with the current widely used method: Bicubic ESRGAN and SRGAN, our method has better reconstruction quality and higher PSNR/SSIM score. CONCLUSION: We used DnCNN to denoise the CMR image, and then using the improved SRGAN to perform super-resolution reconstruction of the denoised image, we can solve the problem of high noise and artifacts that cause the cardiac image to be reconstructed incorrectly during super-resolution.