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Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils.
Kimishima, Yusuke; Misaka, Tomofumi; Yokokawa, Tetsuro; Wada, Kento; Ueda, Koki; Sugimoto, Koichi; Minakawa, Keiji; Nakazato, Kazuhiko; Ishida, Takafumi; Oshima, Motohiko; Koide, Shuhei; Shide, Kotaro; Shimoda, Kazuya; Iwama, Atsushi; Ikeda, Kazuhiko; Takeishi, Yasuchika.
Afiliación
  • Kimishima Y; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Misaka T; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan. misaka83@fmu.ac.jp.
  • Yokokawa T; Department of Advanced Cardiac Therapeutics, Fukushima Medical University, Fukushima, Japan. misaka83@fmu.ac.jp.
  • Wada K; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Ueda K; Department of Pulmonary Hypertension, Fukushima Medical University, Fukushima, Japan.
  • Sugimoto K; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Minakawa K; Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University, Fukushima, Japan.
  • Nakazato K; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Ishida T; Department of Pulmonary Hypertension, Fukushima Medical University, Fukushima, Japan.
  • Oshima M; Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University, Fukushima, Japan.
  • Koide S; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Shide K; Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.
  • Shimoda K; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Iwama A; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Ikeda K; Department of Gastroenterology and Hematology, University of Miyazaki, Miyazaki, Japan.
  • Takeishi Y; Department of Gastroenterology and Hematology, University of Miyazaki, Miyazaki, Japan.
Nat Commun ; 12(1): 6177, 2021 10 26.
Article en En | MEDLINE | ID: mdl-34702814
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Activinas Tipo II / Janus Quinasa 2 / Hematopoyesis Clonal / Hipertensión Pulmonar / Pulmón / Neutrófilos Tipo de estudio: Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Activinas Tipo II / Janus Quinasa 2 / Hematopoyesis Clonal / Hipertensión Pulmonar / Pulmón / Neutrófilos Tipo de estudio: Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido