[Ex vivo confocal laser scanning microscopy for melanocytic lesions and autoimmune diseases]. / Ex-vivo konfokale Laserscanmikroskopie bei melanozytären Läsionen und Autoimmunerkrankungen.
Hautarzt
; 72(12): 1058-1065, 2021 Dec.
Article
en De
| MEDLINE
| ID: mdl-34705067
ABSTRACT
BACKGROUND:
Ex vivo confocal laser scanning microscopy (CLSM) enables bedside histology and offers the surgeon a direct intraoperative tissue examination.OBJECTIVES:
To determine whether this innovative, ultra-fast diagnostic tool can be expanded beyond nonmelanoma skin cancer, particularly basal cell carcinoma, to other indications including melanocytic lesions and autoimmune diseases. MATERIALS ANDMETHODS:
Review of literature and summary of the current knowledge and experience of the use of ex vivo CLSM in melanocytic lesions and in autoimmune diseases.RESULTS:
Up to date experience of the use of ex vivo CLSM in melanocytic lesions and in autoimmune diseases is limited but promising. Current knowledge on melanocytic lesions in ex vivo CLSM and their examples together with classic ex vivo CLSM features are presented. Previous results on the use of ex vivo CLSM in autoimmune dermatoses are presented, and future application possibilities of ex vivo CLSM are discussed.CONCLUSIONS:
The method is particularly suitable for the rapid examination of basal cell carcinomas during Mohs surgery but could also be used in the future for the intraoperative examination of melanocytic and autoimmune skin lesions.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Enfermedades Autoinmunes
/
Carcinoma Basocelular
Límite:
Humans
Idioma:
De
Revista:
Hautarzt
Año:
2021
Tipo del documento:
Article