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Association of gastro-oesophageal reflux disease and quality of life in patients with chronic rhinosinusitis.
Xu, Yang; Yang, Wen; Song, Yao; Cheng, Danni; Cao, Min; Huang, Jingyue; Ren, Jianjun; Lee, Jong Wook; Hueniken, Katrina; Chen, Yao; Brown, Catherine; Zhang, Yuke; Qiu, Ke; Xu, Wei; Zhao, Yu; Liu, Geoffrey.
Afiliación
  • Xu Y; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Yang W; Medical Oncology and Medical Biophysics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
  • Song Y; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Cheng D; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Cao M; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Huang J; General Affairs Office of Logistic Department, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Ren J; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Lee JW; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Hueniken K; Medical Oncology and Medical Biophysics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
  • Chen Y; Department of Otolaryngology Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
  • Brown C; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Zhang Y; Department of Gastroenterology, Chengdu First People's Hospital, Chengdu, Sichuan, China.
  • Qiu K; Medical Oncology and Medical Biophysics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
  • Xu W; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Zhao Y; Department of Otorhinolaryngology Head and Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China.
  • Liu G; Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Acta Otorhinolaryngol Ital ; 41(5): 450-460, 2021 Oct.
Article en En | MEDLINE | ID: mdl-34734581
OBJECTIVE: We determined the influence of gastro-oesophageal reflux disease (GERD) on quality of life (QOL) before and after functional-endoscopic-sinus-surgery (FESS) for chronic rhinosinusitis (CRS). METHODS: Medically-recalcitrant CRS patients were recruited prior to FESS. GERD was diagnosed endoscopically. QOL was compared between patients with vs without GERD at baseline and one-year post-FESS. RESULTS: Of 187 CRS patients receiving FESS, 40 had GERD. Pre-operative QOL was significantly worse in CRS patients with vs without GERD. Pre-operative GERD health-related QOL (GERD-HRQL) and reflux symptom index (RSI) scores were both correlated with pre-operative SNOT-22 scores. Compared with non-GERD CRS patients, GERD patients demonstrated larger SNOT-22 improvements after FESS, such that post-operative SNOT-22 values were no longer significantly different between GERD and non-GERD groups. However, post-FESS, in patients with CRS without nasal polyps (unlike those with nasal polyps), the GERD (vs non-GERD) group suffered from greater sleep dysfunction and otologic/facial symptoms. CONCLUSIONS: Compared to CRS patients without GERD, those with GERD experienced poorer pre-operative QOL and greater QOL improvement after FESS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sinusitis / Reflujo Gastroesofágico / Rinitis / Pólipos Nasales Tipo de estudio: Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Acta Otorhinolaryngol Ital Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sinusitis / Reflujo Gastroesofágico / Rinitis / Pólipos Nasales Tipo de estudio: Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Acta Otorhinolaryngol Ital Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Italia