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Oromandibular parafunction in chronic graft-versus-host disease: novel association and treatment approach.
Joshi, Purwa; Kiers, Lynette; Evans, Andrew; Ritchie, David; Szer, Jeff; Cruse, Belinda.
Afiliación
  • Joshi P; Department of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Kiers L; Department of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Evans A; Department of Medicine (Royal Melbourne Hospital), Faculty of Medicine, Health and Dentistry, The University of Melbourne, Melbourne, Victoria, Australia.
  • Ritchie D; Department of Neurology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
  • Szer J; Department of Medicine (Royal Melbourne Hospital), Faculty of Medicine, Health and Dentistry, The University of Melbourne, Melbourne, Victoria, Australia.
  • Cruse B; Department of Medicine (Royal Melbourne Hospital), Faculty of Medicine, Health and Dentistry, The University of Melbourne, Melbourne, Victoria, Australia.
Intern Med J ; 51(11): 1950-1953, 2021 Nov.
Article en En | MEDLINE | ID: mdl-34796632
ABSTRACT
Chronic graft-versus-host disease (cGVHD) complicating allogeneic haemopoietic stem cell transplantation rarely involves the nervous system; oromandibular parafunction has not been previously reported. We describe five patients with cGVHD, presenting with bruxism, limitation of mouth opening, jaw locking, pain and masseter hypertrophy. Pathophysiological mechanisms are discussed. Targeted botulinum toxin injections were an effective treatment with minimal side-effects.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / Enfermedad Injerto contra Huésped Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Intern Med J Asunto de la revista: MEDICINA INTERNA Año: 2021 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Células Madre Hematopoyéticas / Enfermedad Injerto contra Huésped Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Intern Med J Asunto de la revista: MEDICINA INTERNA Año: 2021 Tipo del documento: Article País de afiliación: Australia