Cytomegalovirus pneumonia of infants in Africa: a narrative literature review.
Future Microbiol
; 16: 1401-1414, 2021 12.
Article
en En
| MEDLINE
| ID: mdl-34812046
Cytomegalovirus pneumonia has repeatedly been described in the context of HIV-exposed uninfected and HIV-infected infants. Despite its significant role in the etiology of childhood pneumonia, there is still a paucity of literature generally, and specifically in Africa, suggesting that it might be a neglected disease. Emerging evidence highlights the importance of postnatal transmission through breastmilk. The pathogenetic significance of the multiplicity of strains acquired through repeated re-infections in early infancy is unknown. The development of cheap, accurate diagnostic tools and safe, effective antivirals and the maintenance of effective prevention and treatment of pediatric HIV are needed to manage cytomegalovirus pneumonia in low-resource settings.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neumonía
/
Infecciones por VIH
/
Infecciones por Citomegalovirus
Tipo de estudio:
Diagnostic_studies
Límite:
Child
/
Humans
/
Infant
País/Región como asunto:
Africa
Idioma:
En
Revista:
Future Microbiol
Asunto de la revista:
MICROBIOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Sudáfrica
Pais de publicación:
Reino Unido