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The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90.
Wang, Kuan-Chih; Lu, Mei-Chin; Hsu, Kai-Cheng; El-Shazly, Mohamed; Shih, Shou-Ping; Lien, Ssu-Ting; Kuo, Fu-Wen; Yang, Shyh-Chyun; Chen, Chun-Lin; Yang, Yu-Chen S H.
Afiliación
  • Wang KC; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Lu MC; Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan.
  • Hsu KC; National Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
  • El-Shazly M; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
  • Shih SP; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 110, Taiwan.
  • Lien ST; TMU Research Center of Drug Discovery, Taipei Medical University, Taipei 110, Taiwan.
  • Kuo FW; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street, Cairo 11566, Egypt.
  • Yang SC; Department of Pharmaceutical Biology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt.
  • Chen CL; Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University (NSYSU), Kaohsiung 804, Taiwan.
  • Yang YSH; Doctoral Degree Program in Marine Biotechnology, Academia Sinica, Taipei 115, Taiwan.
Molecules ; 26(22)2021 Nov 21.
Article en En | MEDLINE | ID: mdl-34834129
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinonas / Especies Reactivas de Oxígeno / Proteínas HSP90 de Choque Térmico / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quinonas / Especies Reactivas de Oxígeno / Proteínas HSP90 de Choque Térmico / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza