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Peri-implant parameters and bone metabolic markers among water-pipe users treated with photodynamic therapy.
Al-Hamoudi, Nawwaf; Alali, Yasser; Al-Aali, Khulud; Alhumaidan, Abdulkareem A; Heer, Emal; Tanveer, Syeda A; Naseem, Mustafa; Vohra, Fahim; Abduljabbar, Tariq.
Afiliación
  • Al-Hamoudi N; Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia. Electronic address: nalhamoudi@ksu.edu.sa.
  • Alali Y; Department of Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Electronic address: Yalali@ksu.edu.sa.
  • Al-Aali K; Department Of Clinical Dental Sciences, College of Dentistry, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia. Electronic address: kaalaali@pnu.edu.sa.
  • Alhumaidan AA; Preventive dental sciences department, College of Dentistry, Imam Abdulrahman bin Faisal University. Dammam, Saudi Arabia. Electronic address: aaalhumaidan@iau.edu.sa.
  • Heer E; Department of Pharmacology, Dr Ishrat Ul Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan.
  • Tanveer SA; Department of Operative Dentistry, College of Dentistry, Dow International Dental College, Karachi, Pakistan.
  • Naseem M; Department of Community and Preventive Dental Sciences, College of Dentistry, Dow International Dental College, Karachi, Pakistan. Electronic address: mustafa.naseem@duhs.edu.pk.
  • Vohra F; Department of Prosthetic Dental Science, College of Dentistry, King Saud University; Research Chair for Biological Research in Dental Health, College of Dentistry, Riyadh 11545, Saudi Arabia. Electronic address: fvohra@ksu.edu.sa.
  • Abduljabbar T; Department of Prosthetic Dental Science, College of Dentistry, King Saud University; Research Chair for Biological Research in Dental Health, College of Dentistry, Riyadh 11545, Saudi Arabia. Electronic address: tajabbar@ksu.edu.sa.
Photodiagnosis Photodyn Ther ; 37: 102655, 2022 Mar.
Article en En | MEDLINE | ID: mdl-34852310
AIM: The study aimed to evaluate the efficacy of Mechanical debridement (MD) with and without adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri­implantitis among waterpipe smokers (WPS) and non-smokers with peri­implantitis MATERIAL AND METHODS: Participants were stratified into two groups. Group 1: Subjects who smoked water pipes for the last 2 years with peri­implant disease were treated with aPDT adjunct to MD and group 2: Participants who did not use water pipes in the last 2 years but have periimplantitis (controls) were treated with MD only. Participants were scrutinized with peri­implantitis (PI) in one dental implant at least based on the inclusion and exclusion criteria. Using structured questionnaire information was gathered from participants. All participants underwent mechanical debridement (MD). Participants of WPS underwent antimicrobial photodynamic therapy (aPDT). Peri implant inflammatory parameters (PI, BI, PD, and CBL) were assessed in all participant at baseline, 3 months and 6 months follow-up. Periimplant sulcular fluid was collected for assessment of bone metabolic biomarkers RANK-L and OPG. For immunological and clinical peri­implant parameters analysis of variance (ANOVA) and Kruskal-Wallis test were used. For multiple comparisons, Bonferroni post hoc test was deployed. RESULTS: Clinical periodontal parameters at baseline were significantly different in the control group PI (49.8 ± 10.5), BI(46.8 ± 7.7), and PD (5.0 ± 1.8) compared to WPS PI (56.1 ± 12.0), BI (40.9 ± 8.3), and PD (5.6 ± 1.5) (p < 0.05). At 3 months follow-up after PDT, PI (19.1 ± 7.7) and PD (3.9 ± 1.4) were significantly lower in the control group compared to WPS group PI (23.5 ± 8.4) and PD (4.5 ± 1.2) (p < 0.05). Whereas, BI of control (16.3 ± 6.8) and WPS group (17.1 ± 5.3) at 3 months follow-up was comparable (p > 0.05). At six months follow up following PDT, PI (15.7 ± 5.5) and PD (3.4 ± 1.2) was significantly lower in the control group compared to participants with water piped users PI (18.6 ± 7.4) and PD (3.9 ± 1.3) (p < 0.05). No significant difference was noted in BI in both groups (p > 0.05). Participants treated with PDT adjunct to MD demonstrated significantly reduced mean RANK-L levels at both 3 and 6 months (p<0.05). CONCLUSION: aPDT adjunctive to MD improved periodontal parameters i.e., plaque index, pocket depth, and crestal bone loss along with metabolic marker RANK-L in water pipe smokers compared to non piped smokers.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Periimplantitis Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: Photodiagnosis Photodyn Ther Asunto de la revista: DIAGNOSTICO POR IMAGEM / TERAPEUTICA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Periimplantitis Tipo de estudio: Qualitative_research Límite: Humans Idioma: En Revista: Photodiagnosis Photodyn Ther Asunto de la revista: DIAGNOSTICO POR IMAGEM / TERAPEUTICA Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos