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Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects.
Junker, Louis H; Li, Biaoru; Zhu, Xingguo; Koti, Sivanagireddy; Cerbone, Ryan E; Hendrick, Clifford L; Sangerman, Jose; Perrine, Susan; Pace, Betty S.
Afiliación
  • Junker LH; Cetya Therapeutics, Fort Collins, CO 80526, United States of America.
  • Li B; Department of Pediatrics, Augusta University, Augusta, GA 30912, United States of America.
  • Zhu X; Department of Pediatrics, Augusta University, Augusta, GA 30912, United States of America.
  • Koti S; Cetya Therapeutics, Fort Collins, CO 80526, United States of America.
  • Cerbone RE; Cetya Therapeutics, Fort Collins, CO 80526, United States of America.
  • Hendrick CL; Cetya Therapeutics, Fort Collins, CO 80526, United States of America.
  • Sangerman J; Departments of Pharmacology and Experimental Therapeutics, Medicine, Pediatrics, Boston University School of Medicine, Boston, MA 02118, United States of America; Phoenicia BioScience Inc, Weston, MA 02493, United States of America.
  • Perrine S; Departments of Pharmacology and Experimental Therapeutics, Medicine, Pediatrics, Boston University School of Medicine, Boston, MA 02118, United States of America; Phoenicia BioScience Inc, Weston, MA 02493, United States of America.
  • Pace BS; Department of Pediatrics, Augusta University, Augusta, GA 30912, United States of America. Electronic address: bpace@augusta.edu.
Blood Cells Mol Dis ; 93: 102626, 2022 03.
Article en En | MEDLINE | ID: mdl-34856533
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gamma-Globinas / Anemia de Células Falciformes Límite: Humans Idioma: En Revista: Blood Cells Mol Dis Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gamma-Globinas / Anemia de Células Falciformes Límite: Humans Idioma: En Revista: Blood Cells Mol Dis Asunto de la revista: HEMATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos