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FARS2 deficiency in Drosophila reveals the developmental delay and seizure manifested by aberrant mitochondrial tRNA metabolism.
Fan, Wenlu; Jin, Xiaoye; Xu, Man; Xi, Yongmei; Lu, Weiguo; Yang, Xiaohang; Guan, Min-Xin; Ge, Wanzhong.
Afiliación
  • Fan W; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
  • Jin X; Institute of Genetics, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
  • Xu M; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China.
  • Xi Y; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
  • Lu W; Institute of Genetics, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
  • Yang X; Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, China.
  • Guan MX; Division of Human Reproduction and Developmental Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
  • Ge W; Institute of Genetics, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
Nucleic Acids Res ; 49(22): 13108-13121, 2021 12 16.
Article en En | MEDLINE | ID: mdl-34878141
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilalanina-ARNt Ligasa / Convulsiones / ARN de Transferencia / Discapacidades del Desarrollo / Proteínas de Drosophila / Proteínas Mitocondriales / Drosophila melanogaster / Mutación Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fenilalanina-ARNt Ligasa / Convulsiones / ARN de Transferencia / Discapacidades del Desarrollo / Proteínas de Drosophila / Proteínas Mitocondriales / Drosophila melanogaster / Mutación Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2021 Tipo del documento: Article País de afiliación: China