The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy.

Adimulam, Theolan; Arumugam, Thilona; Foolchand, Ashmika; Ghazi, Terisha; Chuturgoon, Anil A

Adimulam, Theolan; Arumugam, Thilona; Foolchand, Ashmika; Ghazi, Terisha; Chuturgoon, Anil A.

Afiliación

Adimulam T; Department of Medical Biochemistry, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Arumugam T; Department of Medical Biochemistry, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Foolchand A; Department of Medical Biochemistry, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Ghazi T; Department of Medical Biochemistry, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.
Chuturgoon AA; Department of Medical Biochemistry, School of Laboratory Medicine and Medical Science, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban 4041, South Africa.

Int J Mol Sci ; 22(23)2021 Nov 30.

Article en En | MEDLINE | ID: mdl-34884764

Asunto(s)

Inhibidores de Histona Desacetilasas/farmacología; Neoplasias/tratamiento farmacológico; Compuestos de Organoselenio/farmacología; Acetilación/efectos de los fármacos; Sistemas de Liberación de Medicamentos; Epigénesis Genética/efectos de los fármacos; Código de Histonas/efectos de los fármacos; Código de Histonas/genética; Inhibidores de Histona Desacetilasas/síntesis química; Inhibidores de Histona Desacetilasas/metabolismo; Histona Desacetilasas/metabolismo; Histonas/metabolismo; Humanos; Terapia Molecular Dirigida; Nanopartículas; Neoplasias/genética; Neoplasias/metabolismo; Compuestos de Organoselenio/síntesis química; Compuestos de Organoselenio/metabolismo; Procesamiento Proteico-Postraduccional/efectos de los fármacos

Palabras clave

cancer; histone deacetylation; methylselenocysteine; organoselenium compounds; selenocysteine; selenomethionine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Organoselenio / Inhibidores de Histona Desacetilasas / Neoplasias Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Suiza

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