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EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway.
Qi, Xueju; Zhang, Shuna; Chen, Zekun; Wang, Lijun; Zhu, Wenyong; Yin, Chuanjin; Fan, Junting; Wu, Xiaochen; Wang, Jing; Guo, Chuanlong.
Afiliación
  • Qi X; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
  • Zhang S; The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250011, China.
  • Chen Z; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
  • Wang L; Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China.
  • Zhu W; Department of Thoracic Surgery, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, China.
  • Yin C; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
  • Fan J; Department of Pharmaceutical Analysis, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.
  • Wu X; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
  • Wang J; Department of Biology Science and Technology, Baotou Teacher's College, Baotou, 014030, China. Electronic address: vicwj@163.com.
  • Guo C; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China. Electronic address: guochuanlong@qust.edu.cn.
Chem Biol Interact ; 352: 109773, 2022 Jan 25.
Article en En | MEDLINE | ID: mdl-34902296
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Compuestos de Bencilideno / Inhibidores de la Angiogénesis / Factor 4E Eucariótico de Iniciación / Factor 4G Eucariótico de Iniciación / Hidrazinas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiazoles / Compuestos de Bencilideno / Inhibidores de la Angiogénesis / Factor 4E Eucariótico de Iniciación / Factor 4G Eucariótico de Iniciación / Hidrazinas / Neoplasias Pulmonares / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda