MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway.

Luzwick, Jessica W; Dombi, Eszter; Boisvert, Rebecca A; Roy, Sunetra; Park, Soyoung; Kunnimalaiyaan, Selvi; Goffart, Steffi; Schindler, Detlev; Schlacher, Katharina

Luzwick, Jessica W; Dombi, Eszter; Boisvert, Rebecca A; Roy, Sunetra; Park, Soyoung; Kunnimalaiyaan, Selvi; Goffart, Steffi; Schindler, Detlev; Schlacher, Katharina.

Afiliación

Luzwick JW; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Dombi E; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Boisvert RA; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Roy S; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Park S; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Kunnimalaiyaan S; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.
Goffart S; Department of Environmental and Biological Sciences, University of Eastern Finland, Joensuu, Finland.
Schindler D; Institut für Humangenetik, University of Würzburg, Würzburg, Germany.
Schlacher K; Department of Cancer Biology, UT MD Anderson Cancer Center, Houston, TX, USA.

Sci Adv ; 7(51): eabf9441, 2021 Dec 17.

Article en En | MEDLINE | ID: mdl-34910513

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Sci Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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