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Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy.
Bochem, Jonas; Zelba, Henning; Spreuer, Janine; Amaral, Teresa; Wagner, Nikolaus B; Gaissler, Andrea; Pop, Oltin T; Thiel, Karolin; Yurttas, Can; Soffel, Daniel; Forchhammer, Stephan; Sinnberg, Tobias; Niessner, Heike; Meier, Friedegund; Terheyden, Patrick; Königsrainer, Alfred; Garbe, Claus; Flatz, Lukas; Pawelec, Graham; Eigentler, Thomas K; Löffler, Markus W; Weide, Benjamin; Wistuba-Hamprecht, Kilian.
Afiliación
  • Bochem J; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Zelba H; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Spreuer J; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Amaral T; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Wagner NB; Department of Dermatology, Venereology, Allergology, Kantonsspital St. Gallen, St. Gallen, Switzerland
  • Gaissler A; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Pop OT; Institute for Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Thiel K; Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany.
  • Yurttas C; Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany.
  • Soffel D; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Forchhammer S; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Sinnberg T; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Niessner H; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Meier F; Skin Cancer Center at the University Cancer Centre and National Center for Tumor Diseases Dresden; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany.
  • Terheyden P; Department of Dermatology, University of Lübeck, Lübeck, Germany.
  • Königsrainer A; Department of General, Visceral and Transplant Surgery, University Hospital, Tübingen, Germany.
  • Garbe C; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) Partner Site Tübingen, Tübingen, Germany.
  • Flatz L; Cluster of Excellence iFIT (EXC 2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany.
  • Pawelec G; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Eigentler TK; Department of Dermatology, University Medical Center, Tübingen, Germany.
  • Löffler MW; Health Sciences North Research Institute of Canada, Sudbury, Ontario, Canada.
  • Weide B; Department of Immunology, University of Tübingen, Tübingen, Germany.
  • Wistuba-Hamprecht K; Department of Dermatology, University Medical Center, Tübingen, Germany.
J Immunother Cancer ; 9(12)2021 12.
Article en En | MEDLINE | ID: mdl-34933966
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Linfocitos T CD8-positivos / Antígeno MART-1 / Receptor de Muerte Celular Programada 1 / Inhibidores de Puntos de Control Inmunológico / Melanoma / Proteínas de la Membrana / Antígenos de Neoplasias Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores de Tumor / Linfocitos T CD8-positivos / Antígeno MART-1 / Receptor de Muerte Celular Programada 1 / Inhibidores de Puntos de Control Inmunológico / Melanoma / Proteínas de la Membrana / Antígenos de Neoplasias Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido