Your browser doesn't support javascript.
loading
Emerging Therapeutic Agents for Colorectal Cancer.
Nalli, Marianna; Puxeddu, Michela; La Regina, Giuseppe; Gianni, Stefano; Silvestri, Romano.
Afiliación
  • Nalli M; Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185 Rome, Italy.
  • Puxeddu M; Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185 Rome, Italy.
  • La Regina G; Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185 Rome, Italy.
  • Gianni S; Department of Biochemical Sciences "Rossi Fanelli", Institute of Biology and Molecular Pathology of CNR, Sapienza University of Rome, 00185 Rome, Italy.
  • Silvestri R; Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185 Rome, Italy.
Molecules ; 26(24)2021 Dec 09.
Article en En | MEDLINE | ID: mdl-34946546
There are promising new therapeutic agents for CRC patients, including novel small-molecule inhibitors and immune checkpoint blockers. We focused on emerging CRC's therapeutic agents that have shown the potential for progress in clinical practice. This review provides an overview of tyrosine kinase inhibitors targeting VEGF and KIT, BRAF and MEK inhibitors, TLR9 agonist, STAT3 inhibitors, and immune checkpoint blockers (PD1/PDL-1 inhibitors), for which recent advances have been reported. These new agents have the potential to provide benefits to CRC patients with unmet medical needs.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Inhibidores de Proteínas Quinasas / Terapia Molecular Dirigida / Proteínas de Neoplasias Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Inhibidores de Proteínas Quinasas / Terapia Molecular Dirigida / Proteínas de Neoplasias Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza