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Nanotechnology in Cancer Diagnostics and Therapeutics: A Review.
Yadav, Neelam; Dahiya, Twinkle; Chhillar, Anil Kumar; Rana, Jogender Singh; Saini, Hari Mohan.
Afiliación
  • Yadav N; Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Sonipat, Haryana, India.
  • Dahiya T; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, India.
  • Chhillar AK; Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Sonipat, Haryana, India.
  • Rana JS; Centre for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, India.
  • Saini HM; Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Sonipat, Haryana, India.
Curr Pharm Biotechnol ; 23(13): 1556-1568, 2022.
Article en En | MEDLINE | ID: mdl-34951360
Cancer is the uncontrolled proliferation of cells that involves accumulation of genetic mutations by different types of mutagens including physical, chemical, and biological. Consequently, normal cell cycles get interrupted. Immunological assays, histopathological tests, polymerase chain reaction, computed tomography, magnetic resonance, and radiation therapy are some conventional techniques for cancer diagnostics. However, these techniques are not only expensive, time-consuming, tedious but also toxic to healthy cells. Therefore, these limitations are overcome by nanodevices that show high sensitivity, selectivity, rapidity, and cost-effectiveness in the detection of cancer biomarkers. Electrochemical biosensors are more efficient in the early diagnosis of cancers that help in patients' effective and timely treatment. Distinct types of nanotools viz. inorganic, organic, and polymeric nanomaterials are used in cancer therapeutics. Nano approaches have shown many advantages: they are site-specific, require meager amounts of drugs, limited toxicity, avoid drug resistance, and are more efficient, sensitive, and reliable. Therefore, future research should focus on developing highly inventive nanotools for the diagnosis and therapeutics of cancers.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Neoplasias Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Curr Pharm Biotechnol Asunto de la revista: BIOTECNOLOGIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Técnicas Biosensibles / Neoplasias Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Curr Pharm Biotechnol Asunto de la revista: BIOTECNOLOGIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos