Ameliorative effect of flavonoid-rich extracts from <i>Gongronema latifolium</i> against diabetic cardiomyopathy via serpin A<sub>3</sub> and socs3-a in streptozocin treated rats.

Oyinloye, Babatunji Emmanuel; Ajiboye, Basiru Olaitan; Johnson, Oluwafolakemi; Owolabi, Olutunmise Victoria; Ejeje, Jerius Nkwuda; Brai, Bartholomew I C; Omotuyi, Olaposi Idowu

Ameliorative effect of flavonoid-rich extracts from Gongronema latifolium against diabetic cardiomyopathy via serpin A₃ and socs3-a in streptozocin treated rats.

Oyinloye, Babatunji Emmanuel; Ajiboye, Basiru Olaitan; Johnson, Oluwafolakemi; Owolabi, Olutunmise Victoria; Ejeje, Jerius Nkwuda; Brai, Bartholomew I C; Omotuyi, Olaposi Idowu.

Afiliación

Oyinloye BE; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Ajiboye BO; Institute of Drug Research and Development, SE Bogoro Center, Afe Babalola University, Ado-Ekiti, Nigeria.
Johnson O; Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, South Africa.
Owolabi OV; Institute of Drug Research and Development, SE Bogoro Center, Afe Babalola University, Ado-Ekiti, Nigeria.
Ejeje JN; Phytomedicine and Molecular Toxicology Research Laboratory, Department of Biochemistry, Federal University Oye-Ekiti, Oye-Ekiti, Nigeria.
Brai BIC; Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratories, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.
Omotuyi OI; Medical Biochemistry Unit, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria.

Biomarkers ; 27(2): 169-177, 2022 Mar.

Article en En | MEDLINE | ID: mdl-34951557

Asunto(s)

Apocynaceae; Diabetes Mellitus Experimental; Cardiomiopatías Diabéticas; Serpinas; Animales; Apocynaceae/metabolismo; Glucemia/metabolismo; Diabetes Mellitus Experimental/tratamiento farmacológico; Diabetes Mellitus Experimental/metabolismo; Cardiomiopatías Diabéticas/tratamiento farmacológico; Flavonoides/farmacología; Flavonoides/uso terapéutico; Humanos; Hipoglucemiantes/farmacología; Hipoglucemiantes/uso terapéutico; Extractos Vegetales/farmacología; Ratas; Ratas Wistar; Estreptozocina/efectos adversos; Proteína 3 Supresora de la Señalización de Citocinas

Palabras clave

Isolate; antioxidant enzymes; flavonoid; gene expression; histology; lipid profiles

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serpinas / Apocynaceae / Diabetes Mellitus Experimental / Cardiomiopatías Diabéticas Límite: Animals / Humans Idioma: En Revista: Biomarkers Asunto de la revista: BIOQUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Nigeria

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