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New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
Milano, Shawn K; Huang, Qingqiu; Nguyen, Thuy-Tien T; Ramachandran, Sekar; Finke, Aaron; Kriksunov, Irina; Schuller, David J; Szebenyi, D Marian; Arenholz, Elke; McDermott, Lee A; Sukumar, N; Cerione, Richard A; Katt, William P.
Afiliación
  • Milano SK; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, USA.
  • Huang Q; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • Nguyen TT; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, USA.
  • Ramachandran S; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, USA.
  • Finke A; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • Kriksunov I; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • Schuller DJ; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • Szebenyi DM; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • Arenholz E; Cornell High Energy Synchrotron Source (CHESS), Cornell University, Ithaca, New York, USA.
  • McDermott LA; Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Drug Discovery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Sukumar N; Department of Chemistry and Center for Informatics, Shiv Nadar University, Gautam Buddha Nagar, Uttar Pradesh, India.
  • Cerione RA; Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, USA; Department of Molecular Medicine, Cornell University, Ithaca, New York, USA. Electronic address: rac1@cornell.edu.
  • Katt WP; Department of Molecular Medicine, Cornell University, Ithaca, New York, USA.
J Biol Chem ; 298(2): 101535, 2022 02.
Article en En | MEDLINE | ID: mdl-34954143
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfuros / Tiadiazoles / Inhibidores Enzimáticos / Glutaminasa / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sulfuros / Tiadiazoles / Inhibidores Enzimáticos / Glutaminasa / Neoplasias Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos