<i>Aeromonas hydrophila</i> inhibits autophagy triggering cytosolic translocation of mtDNA which activates the pro-apoptotic caspase-1/IL-1ß-nitric oxide axis in headkidney macrophages.

Kumar, Manmohan; Shelly, Asha; Dahiya, Priyanka; Ray, Atish; Mazumder, Shibnath

Aeromonas hydrophila inhibits autophagy triggering cytosolic translocation of mtDNA which activates the pro-apoptotic caspase-1/IL-1ß-nitric oxide axis in headkidney macrophages.

Kumar, Manmohan; Shelly, Asha; Dahiya, Priyanka; Ray, Atish; Mazumder, Shibnath.

Afiliación

Kumar M; Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, India.
Shelly A; Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, India.
Dahiya P; Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, India.
Ray A; Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, India.
Mazumder S; Immunobiology Laboratory, Department of Zoology, University of Delhi, Delhi, India.

Virulence ; 13(1): 60-76, 2022 12.

Article en En | MEDLINE | ID: mdl-34967692

Asunto(s)

Aeromonas hydrophila; Interleucina-1beta/metabolismo; Óxido Nítrico; Aeromonas hydrophila/genética; Animales; Apoptosis; Autofagia; Caspasa 1/metabolismo; Citosol/metabolismo; ADN Mitocondrial/metabolismo; Macrófagos; Mitocondrias/metabolismo; Óxido Nítrico/metabolismo; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

Aeromonas hydrophila; IL-1ß; apoptosis; autophagy; caspase-1; er-stress; head kidney macrophage; mtDNA; mtROS

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aeromonas hydrophila / Interleucina-1beta / Óxido Nítrico Límite: Animals Idioma: En Revista: Virulence Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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