Desmoplastic Small Round Cell Tumor in a Pregnant Woman: A Case Report and Literature Review.
Yale J Biol Med
; 94(4): 613-622, 2021 12.
Article
en En
| MEDLINE
| ID: mdl-34970100
ABSTRACT
Background:
Desmoplastic small round cell tumor (DSRCT) is an aggressive malignant tumor commonly found in young men; most occurs in the abdominal cavity. Here we conducted an in-depth analysis of a pregnant patient in our hospital and explored all the case information in the literature on small round cell carcinoma of women. Case presentation A 27-year-old pregnant woman underwent tumor resection in our hospital at 29 weeks gestational age for a large progressive shoulder lump. The postoperative pathology showed that the mass was a DSRCT. Genetic testing found no fusion gene. At 36 weeks gestation, a painful mass was found in the breast and proved to be a metastatic focus of the desmoplastic small round cell tumor. Twenty days after a successful cesarean section at 40 weeks gestation, she received the VAC-IE chemotherapy regimen, successfully completed the first course, but when awaiting the next chemotherapy, unfortunately, the patient died during follow-up due to tumor recurrence and metastasis.Conclusion:
The treatment of DSRCT in pregnant women requires a multidisciplinary consultation, and the treatment and examination during pregnancy are subject to many constraints, which may have a negative impact on the patient's prognosis. Also, a review of the literature found that there is still no standard treatment protocol for DSRCT, and its prognosis in female patients is independent of age and tissue origin.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mujeres Embarazadas
/
Tumor Desmoplásico de Células Pequeñas Redondas
Tipo de estudio:
Guideline
/
Prognostic_studies
Límite:
Adult
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Female
/
Humans
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Male
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Pregnancy
Idioma:
En
Revista:
Yale J Biol Med
Año:
2021
Tipo del documento:
Article