Activation by cleavage of the epithelial Na<sup>+</sup> channel &#945; and Î³ subunits independently coevolved with the vertebrate terrestrial migration.

Wang, Xue-Ping; Balchak, Deidra M; Gentilcore, Clayton; Clark, Nathan L; Kashlan, Ossama B

Activation by cleavage of the epithelial Na⁺ channel α and Î³ subunits independently coevolved with the vertebrate terrestrial migration.

Wang, Xue-Ping; Balchak, Deidra M; Gentilcore, Clayton; Clark, Nathan L; Kashlan, Ossama B.

Afiliación

Wang XP; Department of Medicine, University of Pittsburgh, Pittsburgh, United States.
Balchak DM; Department of Medicine, University of Pittsburgh, Pittsburgh, United States.
Gentilcore C; Department of Medicine, University of Pittsburgh, Pittsburgh, United States.
Clark NL; Department of Human Genetics, University of Utah, Salt Lake City, United States.
Kashlan OB; Department of Medicine, University of Pittsburgh, Pittsburgh, United States.

Elife ; 112022 01 05.

Article en En | MEDLINE | ID: mdl-34984981

Asunto(s)

Canales Epiteliales de Sodio/genética; Evolución Molecular; Peces/genética; Xenopus laevis/genética; Proteínas Anfibias/genética; Proteínas Anfibias/metabolismo; Animales; Canales Epiteliales de Sodio/metabolismo; Proteínas de Peces/genética; Proteínas de Peces/metabolismo; Peces/metabolismo; Xenopus laevis/metabolismo

Palabras clave

E. calabaricus; N. forsteri; epithelial Na+ channel; evolutionary biology; furin; proteolytic activation; vertebrate land invasion; xenopus

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Xenopus laevis / Evolución Molecular / Canales Epiteliales de Sodio / Peces Límite: Animals Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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