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Distribution and volume analysis of early hemorrhagic contusions by MRI after traumatic brain injury: a preliminary report of the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx).
La Rocca, Marianna; Barisano, Giuseppe; Bennett, Alexis; Garner, Rachael; Engel, Jerome; Gilmore, Emily J; McArthur, David L; Rosenthal, Eric; Stanis, James; Vespa, Paul; Willyerd, Frederick; Zimmermann, Lara L; Toga, Arthur W; Duncan, Dominique.
Afiliación
  • La Rocca M; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA. marianna.larocca@loni.usc.edu.
  • Barisano G; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Bennett A; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Garner R; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Engel J; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Gilmore EJ; Comprehensive Epilepsy Center, Department of Neurology, Yale University, New Haven, CT, USA.
  • McArthur DL; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Rosenthal E; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Stanis J; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Vespa P; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Willyerd F; Phoenix Children's Hospital, Phoenix, AZ, USA.
  • Zimmermann LL; University of California Davis Medical Center, Sacramento, CA, USA.
  • Toga AW; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
  • Duncan D; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Brain Imaging Behav ; 15(6): 2804-2812, 2021 Dec.
Article en En | MEDLINE | ID: mdl-34985618
Traumatic brain injury (TBI) can produce heterogeneous injury patterns including a variety of hemorrhagic and non-hemorrhagic lesions. The impact of lesion size, location, and interaction between total number and location of contusions may influence the occurrence of seizures after TBI. We report our methodologic approach to this question in this preliminary report of the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx). We describe lesion identification and segmentation of hemorrhagic contusions by early posttraumatic magnetic resonance imaging (MRI). We describe the preliminary methods of manual lesion segmentation in an initial cohort of 32 TBI patients from the EpiBioS4Rx cohort and the preliminary association of hemorrhagic contusion and edema location and volume to seizure incidence.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contusiones / Epilepsia / Lesiones Traumáticas del Encéfalo Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Brain Imaging Behav Asunto de la revista: CEREBRO / CIENCIAS DO COMPORTAMENTO / DIAGNOSTICO POR IMAGEM Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contusiones / Epilepsia / Lesiones Traumáticas del Encéfalo Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Brain Imaging Behav Asunto de la revista: CEREBRO / CIENCIAS DO COMPORTAMENTO / DIAGNOSTICO POR IMAGEM Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos