Amines for brain tomoscintigraphy.
Nucl Med Commun
; 8(7): 581-95, 1987 Jul.
Article
en En
| MEDLINE
| ID: mdl-3500437
ABSTRACT
Amines like N-isopropyl-p-123I-iodoamphetamine (IMP) and hydroxy 123I-iodobenzyl propyl diamine (HIPDM) associated with brain tomoscintigraphy have proved their worth for detecting ischaemic abnormalities. Even though the chemistry of their metabolism and their biodistribution are not fully understood, their application in the study of parenchymal impairment in stroke and reversible ischaemia yields additional information compared to the other methods of imaging like CT or MRI. The concept of a steady state in brain with a wash in/wash out model has been considered especially with IMP, to explain the evolution of the activity pattern with time when comparing early and delayed images. (This review leads to foresee the prognosis of of ischaemic diseases when redistribution is taken into account.)
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Tomografía Computarizada de Emisión
/
Circulación Cerebrovascular
/
Anfetaminas
/
Radioisótopos de Yodo
/
Yodobencenos
Límite:
Humans
Idioma:
En
Revista:
Nucl Med Commun
Año:
1987
Tipo del documento:
Article
País de afiliación:
Francia