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PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice.
de Jong, Laura M; Zhang, Zhengzheng; den Hartog, Yvette; Sijsenaar, Timothy J P; Martins Cardoso, Renata; Manson, Martijn L; Hankemeier, Thomas; Lindenburg, Peter W; Salvatori, Daniela C F; Van Eck, Miranda; Hoekstra, Menno.
Afiliación
  • de Jong LM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Gorlaeus Laboratories, 2333CC, Leiden, The Netherlands.
  • Zhang Z; Analytical Biosciences and Metabolomics, Division of Systems Biomedicine and Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands.
  • den Hartog Y; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Gorlaeus Laboratories, 2333CC, Leiden, The Netherlands.
  • Sijsenaar TJP; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Gorlaeus Laboratories, 2333CC, Leiden, The Netherlands.
  • Martins Cardoso R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Gorlaeus Laboratories, 2333CC, Leiden, The Netherlands.
  • Manson ML; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Gorlaeus Laboratories, 2333CC, Leiden, The Netherlands.
  • Hankemeier T; Analytical Biosciences and Metabolomics, Division of Systems Biomedicine and Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands.
  • Lindenburg PW; Analytical Biosciences and Metabolomics, Division of Systems Biomedicine and Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands.
  • Salvatori DCF; Research Group Metabolomics, Leiden Center for Applied Bioscience, University of Applied Sciences Leiden, Leiden, The Netherlands.
  • Van Eck M; Central Laboratory Animal Facility, Leiden University Medical Center, Leiden, The Netherlands.
  • Hoekstra M; Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Sci Rep ; 12(1): 483, 2022 01 10.
Article en En | MEDLINE | ID: mdl-35013582
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína-Arginina N-Metiltransferasas / Prurito / Triglicéridos / Receptores de LDL / Hígado Graso / Dieta Occidental / Isoquinolinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína-Arginina N-Metiltransferasas / Prurito / Triglicéridos / Receptores de LDL / Hígado Graso / Dieta Occidental / Isoquinolinas Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido