Methodologic implications for rehabilitation research: Differences in heart rate variability introduced by respiration.
PM R
; 14(12): 1483-1489, 2022 12.
Article
en En
| MEDLINE
| ID: mdl-35077032
ABSTRACT
BACKGROUND:
Heart rate variability is a measure of autonomic activity that is growing in popularity as a research outcome. However, despite its increased use, the known effects of respiration on heart rate variability measures are rarely accounted for in rehabilitation medicine research, leading to potential misinterpretation.OBJECTIVE:
To describe the effect that unpaced and paced breathing introduces to heart rate variability measures in a rehabilitation medicine relevant example of individuals with spinal cord injury.DESIGN:
Cross-sectional comparison of heart rate variability during unpaced and paced breathing (0.25 Hz, 15 breaths per minute) within the same individuals during the same lab session.SETTING:
Academic autonomic physiology laboratory.INTERVENTIONS:
Not applicable. MAIN OUTCOMEMEASURES:
Mean low frequency (LF) and high frequency (HF) heart rate variability power, percentage of total power derived from the LF spectrum, LFHF ratio.RESULTS:
Fifty-nine individuals with spinal cord injury completed laboratory assessments using standardized protocols (NCT02139436). In repeated measures within individuals, mean LF power was significantly higher in unpaced breathing compared to paced breathing (1292 vs. 573 ms2 , p < .001). A Bland-Altman plot demonstrated significant positive proportional bias for LF power when comparing unpaced and paced breathing conditions (R2 = 0.39). Mean HF power was similar between unpaced and paced breathing conditions, although there were wide positive and negative differences between measures, leading to notable uncertainty when respiratory confounders were not accounted for. The percentages of total power derived from the LF spectrum and the mean LFHF ratio were both significantly higher for unpaced breathing compared to paced breathing (64 vs. 42%, p < .001; and 3.2 vs. 1.1, p < .001, respectively).CONCLUSION:
Respiration has a significant effect on heart rate variability following spinal cord injury, and not accounting for this has serious consequences for accurate interpretation of unpaced data. Future studies of heart rate variability in rehabilitation medicine should accordingly consider paced breathing.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Traumatismos de la Médula Espinal
/
Investigación en Rehabilitación
Límite:
Humans
Idioma:
En
Revista:
PM R
Asunto de la revista:
MEDICINA FISICA
/
REABILITACAO
/
TRAUMATOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos