Streptomycin sulphate microspheres: formulation and in vivo distribution.
J Microencapsul
; 3(2): 101-8, 1986.
Article
en En
| MEDLINE
| ID: mdl-3508176
ABSTRACT
Albumin and gelatin microspheres of streptomycin sulphate were formulated and their potential as a drug delivery system for a tuberculostatic agent in vivo was evaluated. Biodistribution was determined by i.v. administration of a 99mTc-labelled microsphere suspension to mice. The radioactivity of the lungs was compared with the radioactivity of the liver, spleen, kidney and heart at 10 min, 60 min, 4 h and 24 h post-injection. The percentage accumulated was higher in the lungs than in the other organs for both albumin and gelatin microspheres.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estreptomicina
/
Composición de Medicamentos
Límite:
Animals
Idioma:
En
Revista:
J Microencapsul
Asunto de la revista:
FARMACIA
Año:
1986
Tipo del documento:
Article
País de afiliación:
Turquía