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Cerebrospinal fluid neurofilament light chain levels in CLN2 disease patients treated with enzyme replacement therapy normalise after two years on treatment.
Iwan, Katharina; Patel, Nina; Heslegrave, Amanda; Borisova, Mina; Lee, Laura; Bower, Rebecca; Mole, Sara E; Mills, Philippa B; Zetterberg, Henrik; Mills, Kevin; Gissen, Paul; Heywood, Wendy E.
Afiliación
  • Iwan K; UCL Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Patel N; UCL Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Heslegrave A; NIHR Great Ormond Street Hospital Biomedical Research Centre, University College London, London, WC1N 1EH, UK.
  • Borisova M; UK Dementia Research Institute, University College London, London, WC1E 6BT, UK.
  • Lee L; UK Dementia Research Institute, University College London, London, WC1E 6BT, UK.
  • Bower R; Great Ormond Street Children's Hospital NHS Foundation Trust, London, WC1N 3JH, UK.
  • Mole SE; Great Ormond Street Children's Hospital NHS Foundation Trust, London, WC1N 3JH, UK.
  • Mills PB; UCL Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Zetterberg H; UCL Institute of Child Health, University College London, London, WC1N 1EH, UK.
  • Mills K; NIHR Great Ormond Street Hospital Biomedical Research Centre, University College London, London, WC1N 1EH, UK.
  • Gissen P; UK Dementia Research Institute, University College London, London, WC1E 6BT, UK.
  • Heywood WE; Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
F1000Res ; 10: 614, 2021.
Article en En | MEDLINE | ID: mdl-35106137
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Reemplazo Enzimático / Lipofuscinosis Ceroideas Neuronales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: F1000Res Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Reemplazo Enzimático / Lipofuscinosis Ceroideas Neuronales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: F1000Res Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido