The additional diagnostic value of motor nerve excitability testing in chronic axonal neuropathy.
Clin Neurophysiol Pract
; 7: 27-33, 2022.
Article
en En
| MEDLINE
| ID: mdl-35128215
ABSTRACT
OBJECTIVE:
To explore potential differences in motor nerve excitability testing (NET) variables at group levels between patients with a clinical diagnosis of polyneuropathy (PNP), which did not fulfil diagnostic criteria of conventional nerve conduction studies (NCS) and patients without polyneuropathy. Such differences could support a role for NET in increasing the diagnostic sensitivity of NCS in chronic axonal PNP.METHODS:
Motor NET was performed using the median nerve in patients with a clinical suspicion of PNP in addition to conventional NCS, skin biopsies, corneal confocal microscopy and structured clinical evaluation including scoring of neuropathy symptoms and signs.RESULTS:
Of the 57 patients included, 32 had PNP, half of which had NCS, which fulfilled criteria for PNP (NCS+ PNP). There were no significant differences for any of the NET variables between PNP patients with non-diagnostic conventional NCS (NCS- PNP) and patients without PNP. Rheobase was increased, and Ted (undershoot) and subexcitability were decreased in NCS+ PNP. Sural amplitude, peroneal nerve F-wave latency and tibial nerve F-wave-latency were correlated with subexcitability, and tibial nerve motor amplitude was correlated with rheobase.CONCLUSIONS:
NET was correlated with conventional NCS and no differences were found between NCS- PNP patients and patients without PNP.SIGNIFICANCE:
NET does not seem to offer any additional diagnostic value in chronic mixed etiology neuropathy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Clin Neurophysiol Pract
Año:
2022
Tipo del documento:
Article
País de afiliación:
Dinamarca