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Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Gunasekar, Susheel K; Xie, Litao; Kumar, Ashutosh; Hong, Juan; Chheda, Pratik R; Kang, Chen; Kern, David M; My-Ta, Chau; Maurer, Joshua; Heebink, John; Gerber, Eva E; Grzesik, Wojciech J; Elliot-Hudson, Macaulay; Zhang, Yanhui; Key, Phillip; Kulkarni, Chaitanya A; Beals, Joseph W; Smith, Gordon I; Samuel, Isaac; Smith, Jessica K; Nau, Peter; Imai, Yumi; Sheldon, Ryan D; Taylor, Eric B; Lerner, Daniel J; Norris, Andrew W; Klein, Samuel; Brohawn, Stephen G; Kerns, Robert; Sah, Rajan.
Afiliación
  • Gunasekar SK; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Xie L; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Kumar A; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Hong J; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Chheda PR; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa, College of Pharmacy, Iowa City, IA, USA.
  • Kang C; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Kern DM; Department of Molecular & Cell Biology, University of California Berkeley, Berkeley, CA, USA.
  • My-Ta C; Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA, USA.
  • Maurer J; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Heebink J; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Gerber EE; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Grzesik WJ; Department of Molecular & Cell Biology, University of California Berkeley, Berkeley, CA, USA.
  • Elliot-Hudson M; Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA, USA.
  • Zhang Y; Stead Family Department of Pediatrics, Endocrinology and Diabetes Division, Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
  • Key P; Department of Internal Medicine, Cardiovascular Division, University of Iowa, Iowa City, IA, USA.
  • Kulkarni CA; Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, China.
  • Beals JW; Department of Internal Medicine, Cardiovascular Division, Washington University School of Medicine, St. Louis, MO, USA.
  • Smith GI; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa, College of Pharmacy, Iowa City, IA, USA.
  • Samuel I; Center for Human Nutrition, Washington University School of Medicine, St. Louis, USA.
  • Smith JK; Center for Human Nutrition, Washington University School of Medicine, St. Louis, USA.
  • Nau P; Department of Surgery, University of Iowa, Carver College of Medicine, Iowa City, IA, USA.
  • Imai Y; Department of Surgery, University of Iowa, Carver College of Medicine, Iowa City, IA, USA.
  • Sheldon RD; Department of Surgery, University of Iowa, Carver College of Medicine, Iowa City, IA, USA.
  • Taylor EB; Department of Internal Medicine, Cardiovascular Division, University of Iowa, Iowa City, IA, USA.
  • Lerner DJ; Department of Biochemistry, University of Iowa, Iowa City, IA, USA.
  • Norris AW; Department of Biochemistry, University of Iowa, Iowa City, IA, USA.
  • Klein S; Senseion Therapeutics Inc, BioGenerator Labs, St Louis, MO, USA.
  • Brohawn SG; Stead Family Department of Pediatrics, Endocrinology and Diabetes Division, Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
  • Kerns R; Center for Human Nutrition, Washington University School of Medicine, St. Louis, USA.
  • Sah R; Department of Molecular & Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Nat Commun ; 13(1): 784, 2022 02 10.
Article en En | MEDLINE | ID: mdl-35145074
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Enfermedad del Hígado Graso no Alcohólico / Control Glucémico / Proteínas de la Membrana Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Enfermedad del Hígado Graso no Alcohólico / Control Glucémico / Proteínas de la Membrana Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos