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Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study.
Bershteyn, Anna; Dahl, Angela M; Dong, Tracy Q; Deming, Meagan E; Celum, Connie L; Chu, Helen Y; Kottkamp, Angelica C; Greninger, Alexander L; Hoffman, Risa M; Jerome, Keith R; Johnston, Christine M; Kissinger, Patricia J; Landovitz, Raphael J; Laufer, Miriam K; Luk, Alfred; Neuzil, Kathleen M; Paasche-Orlow, Michael K; Pitts, Robert A; Schwartz, Mark D; Stankiewicz Karita, Helen C; Thorpe, Lorna E; Wald, Anna; Zheng, Crystal Y; Wener, Mark H; Barnabas, Ruanne V; Brown, Elizabeth R.
Afiliación
  • Bershteyn A; Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
  • Dahl AM; Department of Biostatistics, University of Washington, Seattle, Washington, USA.
  • Dong TQ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Deming ME; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Celum CL; International Clinical Research Center and Department of Global Health, University of Washington, Seattle, Washington, USA.
  • Chu HY; Department of Medicine and Department of Epidemiology, University of Washington, Seattle, Washington, USA.
  • Kottkamp AC; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
  • Greninger AL; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Hoffman RM; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
  • Jerome KR; Department of Medicine and Division of Infectious Diseases, University of California, Los Angeles, California, USA.
  • Johnston CM; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Kissinger PJ; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
  • Landovitz RJ; Department of Medicine and Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
  • Laufer MK; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
  • Luk A; Center for Clinical AIDS Research & Education, University of California, Los Angeles, California, USA.
  • Neuzil KM; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Paasche-Orlow MK; John W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
  • Pitts RA; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
  • Schwartz MD; Department of Medicine and Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Stankiewicz Karita HC; Department of Medicine and Division of Infectious Diseases, NYC Health & Hospitals/Bellevue, New York, New York, USA.
  • Thorpe LE; Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
  • Wald A; Department of Medicine, University of Washington, Seattle, Washington, USA.
  • Zheng CY; Department of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
  • Wener MH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Barnabas RV; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
  • Brown ER; Department of Medicine, Department of Epidemiology, Seattle, Washington, USA.
Clin Infect Dis ; 75(1): e1180-e1183, 2022 08 24.
Article en En | MEDLINE | ID: mdl-35152299
Coronavirus disease 2019 symptom definitions rarely include symptom severity. We collected daily nasal swab samples and symptom diaries from contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case patients. Requiring ≥1 moderate or severe symptom reduced sensitivity to predict SARS-CoV-2 shedding from 60.0% (95% confidence interval [CI], 52.9%-66.7%) to 31.5% (95% CI, 25.7%- 38.0%) but increased specificity from 77.5% (95% CI, 75.3%-79.5%) to 93.8% (95% CI, 92.7%-94.8%).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos