An Insight on the Pathways Involved in Crizotinib and Sunitinib Induced Hepatotoxicity in HepG2 Cells and Animal Model.

Guo, Lin; Tang, Tingli; Fang, Dongmei; Gong, Hui; Zhang, Bikui; Zhou, Yueyin; Zhang, Leiyi; Yan, Miao

Guo, Lin; Tang, Tingli; Fang, Dongmei; Gong, Hui; Zhang, Bikui; Zhou, Yueyin; Zhang, Leiyi; Yan, Miao.

Afiliación

Guo L; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China.
Tang T; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China.
Fang D; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China.
Gong H; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zhang B; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhou Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China.
Zhang L; Orthodontic Department of Xiangya Stomatology Hospital, Central South University, Changsha, China.
Yan M; Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, China.

Front Oncol ; 12: 749954, 2022.

Article en En | MEDLINE | ID: mdl-35155225

Palabras clave

Keap1/Nrf2; apoptosis; crizotinib; hepatotoxicity; liver mitochondrial injury; sunitinib

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Oncol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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