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Positional scanning of natural product hispidol's ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases.
Hassan, Ahmed H E; Kim, Hyeon Jeong; Gee, Min Sung; Park, Jong-Hyun; Jeon, Hye Rim; Lee, Cheol Jung; Choi, Yeonwoo; Moon, Suyeon; Lee, Danbi; Lee, Jong Kil; Park, Ki Duk; Lee, Yong Sup.
Afiliación
  • Hassan AHE; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
  • Kim HJ; Medicinal Chemistry Laboratory, Department of Pharmacy, College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
  • Gee MS; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Park JH; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
  • Jeon HR; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
  • Lee CJ; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
  • Choi Y; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
  • Moon S; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
  • Lee D; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, Seoul, Republic of Korea.
  • Lee JK; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
  • Park KD; Department of Fundamental Pharmaceutical Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
  • Lee YS; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
J Enzyme Inhib Med Chem ; 37(1): 768-780, 2022 Dec.
Article en En | MEDLINE | ID: mdl-35196956
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Compuestos de Bencilideno / Productos Biológicos / Enfermedades Neurodegenerativas / Inflamación / Monoaminooxidasa / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzofuranos / Compuestos de Bencilideno / Productos Biológicos / Enfermedades Neurodegenerativas / Inflamación / Monoaminooxidasa / Inhibidores de la Monoaminooxidasa Límite: Humans Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Reino Unido