Radiomics improves the utility of ADC for differentiation between renal oncocytoma and chromophobe renal cell carcinoma: Preliminary findings.
Actas Urol Esp (Engl Ed)
; 46(3): 167-177, 2022 04.
Article
en En, Es
| MEDLINE
| ID: mdl-35216964
ABSTRACT
OBJECTIVE:
Differentiation between renal oncocytoma (RON) and chromophobe renal cell carcinoma (chRCC) remains challenging. We aimed to assess the accurate apparent diffusion coefficient (ADC) radiomics features in differentiating these tumors. MATERIALS ANDMETHODS:
This single-center retrospective study included 14 patients with histopathologically proven RON (nâ¯=â¯6) and chRCC (nâ¯=â¯8) who underwent magnetic resonance imaging. Features were extracted from ADC maps. Features with an intraclass correlation coefficient >0.90, an intergroup pâ¯<â¯0.01 and interrater differences with normal distribution underwent agreement and receiver operating characteristic curve analyses.RESULTS:
Overall, 6 features qualified for further analysis and Bland-Altman plots revealed acceptable agreement for all. Only 1 first order feature and 5 high order texture features successfully predicted RON with more than 90% sensitivities and specificities more than 80%.CONCLUSION:
Squared mean ADC and certain gray level run length matrix features extracted by radiomics of ADC mapping provide quite high diagnostic precision in terms of distinguishing between RON and chRCC.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carcinoma de Células Renales
/
Adenoma Oxifílico
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Neoplasias Renales
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Female
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Humans
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Male
Idioma:
En
/
Es
Revista:
Actas Urol Esp (Engl Ed)
Año:
2022
Tipo del documento:
Article